However, the mechanism is unclear. Here, we found that FOXP3 + T cells were increased in psoriatic lesions after UVB irradiation ( t ' = 3.7006, P
Book Title: Ultraviolet Irradiation Promotes FOXP3 Transcription Via P53 in Psoriasis
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Published on 2016 by
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Book is About: Psoriasis
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Abstract: The decrease of forkhead box P3‐positive (FOXP3 + ) regulatory T cells (Tregs) causes an immune imbalance with effector T cells in psoriasis. Previous studies have demonstrated that in addition to its known effects on keratinocytes and effector T cells, ultraviolet (UV) irradiation alleviates psoriasis via the upregulation of FOXP3 + Tregs. However, the mechanism is unclear. Here, we found that FOXP3 + T cells were increased in psoriatic lesions after UVB irradiation ( t ' = 3.7006, P
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