Otherwise, abnormal angiogenesis can occur during the pathogenesis of certain \u003cbr\u003e\nchronic diseases such as diabetes, rheumatoid arthritis, \u003cb\u003epsoriasis\u003c/b\u003e and tumor, \u003cbr\u003e\nincluding breast \u003cb\u003ecancer\u003c/b\u003e. The acquisition of the angiogenic phenotype occurs very\u003cbr\u003e\n ...

Book Title: Trends in Angiogenesis Research
Author:Roberta V. Zubar
Published on 2005 by Nova Publishers
ISBN: 9781594544521 / 1594544522
Total Page: 254
Book Category:Medical
Book is About: Psoriasis Cancer

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Angiogenesis -- the growth of new blood vessels -- is an important natural process occurring in the body, both for health and as related to disease. Angiogenesis occurs in the healthy body to help heal wounds and to help restore blood flow to tissues after injury or insult. In females, angiogenesis also occurs during the monthly reproductive cycle (to rebuild the uterus lining, to mature the egg during ovulation) and during pregnancy (to build the placenta, the circulation between mother and foetus). The healthy body controls angiogenesis through a series of |on| and |off| switches. The main |on| switches are known as angiogenesis-stimulating growth factors. The main |off switches| are known as angiogenesis inhibitors. When angiogenic growth factors are produced in excess of angiogenesis inhibitors the balance is tipped in favour of blood vessel growth. When inhibitors are present in excess of stimulators, angiogenesis is stopped. The normal, healthy body maintains a perfect balance of angiogenesis modulators. In general, angiogenesis is |turned off| by the production of more inhibitors than stimulators. Tumour angiogenesis is the proliferation of a network of blood vessels that penetrates into cancerous growths, supplying nutrients and oxygen and removing waste products. Tumour angiogenesis actually starts with cancerous tumour cells releasing molecules that send signals to surrounding normal host tissue. This signalling activates certain genes in the host tissue that, in turn, cause proteins to encourage growth of new blood vessels. This new book examines its angiogenesis within the context of theory and its applications to cancer treatment.

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  2. Trends in Angiogenesis Research published by Nova Publishers since 2005 with ISBNs. The book ISBN 13 Code is 9781594544521 and ISBN 10 Code is 1594544522
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  4. The book has "254 Pages" is Printed at BOOK underMedicalCategory
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