Abstract : Background: Several psoriasis-associated microRNAs have been identified. IL-22 plays a pathogenic role in psoriasis. STAT3-dependent IL-22 signaling and its effects on keratinocytes are negatively regulated by SIRT1 .
Book Title: Relationship Between MicroRNA-369-3p, SIRT1, and IL-22 in Psoriasis Vulgaris
Author:
Published on 2017 by
ISBN: /
Total Page:
Book Category:
Book is About: Psoriasis
Download Relationship Between MicroRNA-369-3p, SIRT1, and IL-22 in Psoriasis Vulgaris eBook
Abstract : Background: Several psoriasis-associated microRNAs have been identified. IL-22 plays a pathogenic role in psoriasis. STAT3-dependent IL-22 signaling and its effects on keratinocytes are negatively regulated by SIRT1 . Objective: To explore the relationship between microRNA-369-3p, SIRT1, and IL-22 in patients with psoriasis. Patients and methods: Twenty-five patients with plaque psoriasis and 25 age and sex matched healthy controls were recruited from the Dermatology Department of Assuit University Hospital in Egypt. Each patient was assessed using the Psoriasis Area and Severity Index score. Serum samples and skin biopsies were obtained from each patient and healthy control to determine relative skin expression levels of microRNA-369-3p and SIRT1 using real-time PCR, and serum levels of IL-22 using enzyme-linked immunosorbent assay. Results: MicroRNA-369-3p demonstrated increased expression in skin samples collected from patients with psoriasis. There were significantly higher serum levels of IL-22 in patients with psoriasis vulgaris than in controls. There was no significant correlation between microRNA-369-3p, SIRT1 expression, and IL-22 levels. Conclusion: MicroRNA-369-3p may play a role in the pathogenesis of psoriasis by regulating the expression of other predicted target genes, but not that of SIRT1 .
Our site presents totally free Psoriasis Information products to download. Relationship Between MicroRNA-369-3p, SIRT1, and IL-22 in Psoriasis Vulgaris would be the one among fantastic e book to have from us, a free ebooks portal, the best free ebooks download library. You will discover and download free ebooks in categories. Zero subscription is essential to download free e-books. We have big number of Psoriasis and ebooks. Each downloadable ebook has a short review with a description. You will find around so many e-books which are able to down load. Get ton of books with us, the open directory for free ebooks and download links, the best place to read ebooks and search free download ebooks.Psoriasis ebooks free
download Relationship Between MicroRNA-369-3p, SIRT1, and IL-22 in Psoriasis Vulgaris ebook as PDF, EPUB, MOBI, AZW and AZW3, FB2, DJVU, LIT, RFT, IBA, LRS, LRF, and LRX.
download ebooks
There are lots of e-books about Relationship Between MicroRNA-369-3p, SIRT1, and IL-22 in Psoriasis Vulgaris that are available to obtain. Thinking of having Relationship Between MicroRNA-369-3p, SIRT1, and IL-22 in Psoriasis Vulgaris ebook? You are in the right place. Download the ebook Relationship Between MicroRNA-369-3p, SIRT1, and IL-22 in Psoriasis Vulgaris by: .
Book Details:
- E-book has been rated from 27 by Google Books for Relationship Between MicroRNA-369-3p, SIRT1, and IL-22 in Psoriasis Vulgaris
- Relationship Between MicroRNA-369-3p, SIRT1, and IL-22 in Psoriasis Vulgaris published by since 2017 with ISBNs. The book ISBN 13 Code is and ISBN 10 Code is
- Reading Mode in Text Status is false and Reading Mode in Image Status is false
- The book has " Pages" is Printed at BOOK under Category
- Rated by Raters and have average rate at ""
- eBook written in en
- Book Preview Address: http://books.google.com/books?id=6yvJvQEACAAJ&dq=Psoriasis&hl=&cd=266&source=gbs_api
Book Preview
The Button is not working? Try The Alternative links for "Relationship Between MicroRNA-369-3p, SIRT1, and IL-22 in Psoriasis Vulgaris by: ":
- Server 2: SECURE LINK